cobosci - biomedical research and drug discovery

Cobo Technologies is a fast growing start-up company based in Copenhagen, Denmark, that develop tools and services based around the CRISPR/Cas9 technology and the powerful IDAA method. The INDEL Profiling Platform was launched in December 2017 and today Cobo Technologies support customers in both Europe, US and Asia, with this advanced INDEL analysis solution including the proprietary INDEL analysis software, ProfileIt and the INDEL profile database, The ProfileIt Repository. Details: Identification of down to single base insertions/deletions (INDELs) in pools and clones. Detection of down to 0.1% INDEL events. Detect large deletions up to 1000bs. Detect small insertions up to 150bs. Fast INDEL profiling in high-throughput format in pools and clones. 96 samples can be analysed in 2 hours. Easy detection of bi-allelic targeting events in single cell clones. Easy analysis of profiles using the INDEL analysis software: ProfileIt Any nuclease system (CRISPR, ZFN, TALEN). Applications: gRNA validation. Selection of pools or/and clones with out-of-frame INDELs. Tag confirmation (up to 150bs). Cas9 kinetics. Cas9 delivery methods. NHEJ inhibitor screening/validation. HDR inhibitor screening/validation. Drug-resistance allele generation (in-frame insertions/deletions) Testimonials: What did you particularly like about this service? The information that the INDEL Profiling Service provided (precise and reproducible quantitation of INDEL formation), the good interaction with COBO Technologies and the nice software (ProfileIt) they developed Senior Scientist, Lundbeck Pharma, Denmark" Highly quantitative, minimal amount of material required, detailed profiling of In/dels, easy to interpret the results, highly accessible and excellent customer service, and reasonable prices VP, RD, NERx BioSciences, US